Muscle wasting and changes in muscle protein metabolism in chronic obstructive pulmonary disease

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Muscle wasting and changes in muscle protein metabolism in chronic obstructive pulmonary disease.

Loss of skeletal muscle mass is now recognised as an important feature of chronic obstructive pulmonary disease (COPD) which contributes to symptoms and influences prognosis. The changes in skeletal muscle remain poorly understood, largely because only a few studies have been performed to define the adaptations in whole body and muscle protein metabolism in COPD. The first sections of this revi...

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Chronic obstructive lung disease (COPD) is a chronic multisystem disease with a considerable burden. One of its most common complications is pulmonary artery hypertension (PAH). It has been demonstrated that the development of PAH is correlated with decreased quality of life and survival. Different medications have been proposed for the treatment of PAH, among which one can name statins. Howeve...

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Growth differentiation factor‐15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wasting in vivo

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2003

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.03.00004608